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Turner Publishing Company - Jack Challem

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181 pages

English

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In Feed Your Genes Right, renowned nutrition expert Jack Challem translates the hugely exciting science of nutrigenomics--which explores the link between nutrition and our own DNA--into practical eating plans and nutritional supplement recommendations for maximizing one's genetic inheritance, slowing the aging process, and reducing the chances of disease. After describing how food and nutrients can help repair flawed or damaged genes, Challem offers specific plans--complete with delicious carb-smart recipes--that target two dozen common or inherited diseases and conditions, including arthritis, cancer, diabetes, fatigue, gluten intolerance, heart disease, and obesity.
Foreword by Kilmer S. McCully, M.D.

Preface.

Acknowledgments.

PART I: THE NUTRITION-GENE CONNECTION.

1. Your Genes Depend on Good Nutrition.

2. DNA Damage, Aging, and Disease.

3. Conflicts between Ancient Genes and Modern Foods.

PART II: GENE-ENHANCING NUTRITIONAL SUPPLEMENTS.

4. Nutrients that Enhance Energy and Prevent DNA Damage.

5. Nutrients That Make and Repair DNA.

6. Nutrients that Protect DNA from Damage.

PART III: GENE-ENHANCING EATING PLANS.

7. Dietary Guidelines for feeding Your Genes Right.

8. Recipes, Menu Plans, and Guidelines for Eating Out.

PART IV: Nutrition Plans for Protecting and Enhancing Your Genes.

9. Stress, Genes, and Nutrition.

10. Nutritional Recommendations for Specific Diseases, A to Z.

Afterword.

Appendix A. Genetic and Nutrition Testing.

Appendix B. Resources for Supplements, Food, and Additional Information.

Selected References.

Index.

Sujets

Santé et bien-être

Diététique

diététique

Nutrition

Fitness

Health

Diet

Informations

Publié par	Turner Publishing Company
Date de parution	27 juillet 2007
Nombre de lectures	1
EAN13	9780470240205
Langue	English

Informations légales : prix de location à la page 0,0748€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

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Feed Your Genes Right
Eat to Turn Off Disease-Causing Genes and Slow Down Aging
Jack Challem

John Wiley Sons, Inc.
Feed Your Genes Right
Feed Your Genes Right
Eat to Turn Off Disease-Causing Genes and Slow Down Aging
Jack Challem

John Wiley Sons, Inc.
Copyright 2005 by Jack Challem. All rights reserved
Published by John Wiley Sons, Inc., Hoboken, New Jersey
Published simultaneously in Canada
Design and composition by Navta Associates, Inc.
No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 646-8600, or on the web at www.copyright.com . Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) 748-6011, fax (201) 748-6008.
Limit of Liability/Disclaimer of Warranty: While the publisher and the author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor the author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.
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Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books. For more information about Wiley products, visit our web site at www.wiley.com .
Library of Congress Cataloging-in-Publication Data:
Challem, Jack.
Feed your genes right : eat to turn off disease-causing genes and slow down aging / Jack Challem.
p. cm.
Includes bibliographical references and index.
ISBN 0-471-47986-1
1. Nutrition-Genetic aspects. 2. DNA damage-Prevention. 3. Diet in disease. I. Title. QP143.7.C48 2005
613.2-dc22
2004024636
Printed in the United States of America
10 9 8 7 6 5 4 3 2 1
I dedicate this book to DeWitt Garrett, who first taught me about the health benefits of vitamins and nutrition.
CONTENTS
Foreword by Kilmer S. McCully, M.D.
Preface
Acknowledgments
PART I The Nutrition-Gene Connection
1 Your Genes Depend on Good Nutrition
2 DNA Damage, Aging, and Disease
3 Conflicts between Ancient Genes and Modern Foods
PART II Gene-Enhancing Nutritional Supplements
4 Nutrients That Enhance Energy and Prevent DNA Damage
5 Nutrients That Make and Repair DNA
6 Nutrients That Protect DNA from Damage
PART III Gene-Enhancing Eating Plans
7 Dietary Guidelines for Feeding Your Genes Right
8 Recipes, Menu Plans, and Guidelines for Eating Out
PART IV Nutrition Plans for Protecting and Enhancing Your Genes
9 Stress, Genes, and Nutrition
10 Nutritional Recommendations for Specific Diseases, A to Z
Afterword
Appendix A Genetic and Nutrition Testing
Appendix B Resources for Supplements, Food, and Additional Information
Selected References
Index
FOREWORD
The study of DNA in heredity and disease has led to a great many heady scientific discoveries and, ironically, to some humbling acknowledgments of ancient medical wisdom.
Scientists discovered nucleic acids, the general chemical building blocks of DNA (deoxyribonucleic acid) and genes, in the 1890s. Within several decades, biochemists and biologists had gained an impressive understanding of how nucleic acids were involved in heredity, and by 1950 experiments with bacteria had proven that DNA transmits inherited traits from one generation to the next.
Perhaps the single most dramatic event to ignite the imagination and enthusiasm of biologists was the 1953 discovery by James Watson and Francis Crick of the double-helix structure of DNA. All that remained, or so it seemed at the time, was to decipher and describe the genetic code in terms of its four-letter chemical alphabet.
But unraveling the details of DNA and its role in health and disease has turned out to be a far more complex and, at times, vexing process. As it turned out, the new millennium coincided with the complete decoding of the human genome, and this catalog of all human genes has led to many new insights into the function of DNA. Unfortunately, the promise of turning these discoveries into practical ways of preventing and treating disease has so far been disappointing. Cardiovascular diseases remain the leading cause of death in the United States and most of the developed world, while the scourge of cancer continues to take its relentless toll despite minor advances in treatment and prevention. Gene therapy has proven dangerous and difficult and has had few significant successes. Despite our current understanding of cancer-causing oncogenes and the details of how genes function, researchers have devised few new and effective therapies for cancer patients.
Quite surprisingly, the promise of improved treatment and prevention of human disease has emerged from an unexpected source: the study of nutrition. This was unanticipated for a couple of reasons. Despite the fact that two thousand years ago, Hippocrates, the father of Western medicine, wrote that food was our best medicine, this idea somehow came to be considered quaint rather than relevant. In addition, modern medicine has often derided and dismissed the role of nutrition in health.
However, increasing numbers of researchers and physicians have begun to acknowledge that the foods we eat lay the foundation for the biochemical milieu of our DNA. For example, the body s production of new DNA, required for health and healing, depends on the presence of many vitamins. The activity of DNA is further influenced by various nutrients intersecting with genetically determined biochemical processes. And the progression of many diseases can often be influenced or ameliorated by careful adjustments in the intake of dietary nutrients.
This is a brave new world-and an exciting one at that-in the fields of both genetics and nutrition. But it has been many years in coming. An excellent example of the interaction of genetics and nutrition was my 1969 discovery of arteriosclerotic vascular disease in children with an inherited disease called homocystinuria. The most common form of homocystinuria is caused by a single abnormal gene, which programs the construction of the enzyme cystathionine beta synthase. This genetic defect results in elevated blood and urine levels of homocysteine, a toxic molecule now recognized in medicine as a risk factor for coronary artery disease and stroke.
The normal activity of the cystathionine beta synthase enzyme activity depends, humbly enough, on vitamin B 6 . Approximately half of all children with this genetic condition respond favorably to large doses of vitamin B 6 with a dramatic lowering of homocysteine levels and a marked reduction in the risk of blood clots and cardiovascular disease. This is but one demonstration of how a genetic disease can be ameliorated by nutritional therapy.
In this important new book on genetics and human disease, the remarkably talented nutrition and health writer Jack Challem clearly explains the importance of nutrition and lifestyle factors in modifying the genetic underpinnings of many human diseases. He draws upon diverse yet authoritative sources to give reliable, sound, effective, and well-reasoned advice. The impressive advances in nutrition and biochemistry over the past several decades parallel the growing understanding of the human genome and the genetic basis of human disease. The merging of these two fields sheds new light on the process of aging and the causes of human degenerative diseases.
Not only does Feed Your Genes Right explain the scientific understanding of nutrition and genetic disease, but also the sound, knowledgeable advice on treatment and prevention given is put into understandable and practical terms in an achievable program of practical dietary improvement. Following the nutritional and lifestyle advice in this book will help prevent the degenerative diseases all too common in our twenty-first-century world.
-Kilmer S. McCully, M.D.
Author, The Homocysteine Revolution and The Heart Revolution
PREFACE
If you re like me, you want to maintain and perhaps improve your health, reduce your chances of developing disease, stay mentally sharp, stay at a normal weight, and remain physically active as you get older. But as I m sure you ve already discovered, there is no shortage of howto health books or programs, frequently offering odd, counterintuitive, or contradictory advice.
How do you make sense of everything you hear?
Today, in the early years of the twenty-first century, medical research is dramatically shifting its focus. Instead of looking only at the physical or biochemical factors that lead to health problems, researchers are gaining a better understanding of the far-reaching roles genes play in determining the risk of disease. Now and in the years to come, the role of genes in health will strongly influence, and perhaps even dominate, recommendations for maintaining health and avoiding disease.