Outliving Cancer , livre ebook

Turner Publishing Company - Robert A. Nagourney

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132 pages

English

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By taking a fresh look at some of medicine's most sacrosanct dictates, Dr. Nagourney has found a better, faster, smarter way to treat even the most complex cancers.

Sujets

Alternative Therapies

Informations

Publié par	Turner Publishing Company
Date de parution	15 octobre 2012
Nombre de lectures	0
EAN13	9781591205500
Langue	English

Informations légales : prix de location à la page 0,0948€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

Extrait

PRAISE FOR
Outliving Cancer
“Dr. Robert A. Nagourney—Nobel-quality researcher and clinical oncologist, extraordinary physician, and creative maverick—is the doctor I’d go to if I had cancer. For decades, with relentless patience, he’s been proving that many supposedly incurable cancers can be killed, with greatly reduced harm to the patient, simply by using agents preselected in the laboratory to kill those specific cancer cells. His explanation of why this works, and why it’s still misunderstood by many physicians, is a triumph of fact and logic over sloppy assumptions and obsolete habits. Everyone who deals with cancer should read this story, marvel at the results, scrutinize the evidence, and help make the change.”
—A MORY B. L OVINS , C HAIRMAN AND C HIEF S CIENTIST , R OCKY M OUNTAIN I NSTITUTE

“In Outliving Cancer , Dr. Robert Nagourney brilliantly presents a riveting story of a functional laboratory test that determines the most effective chemotherapy treatment for an individual patient. Everyone’s cancer is different. This chemosensitivity assay determines what will work in you, not in the average person. This book is a must-read for any physician involved in the diagnosis and/or treatment of cancer and for cancer patients and their family members seeking the most effective therapy. Functional laboratory testing rescued my wife from the certain death. Her survival, now almost fourteen years later, was entirely due to Dr. Nagourney’s identification of a drug combination rarely used in ovarian cancer in 1999, and not recommended by any of the seven gynecologic oncologists she consulted. If you have cancer, this book may save your life!”
—T HOMAS P ANKE , MD, P RESIDENT , S OUTHERN O HIO P ATHOLOGY C ONSULTANTS , I NC .; A UTHOR , P ATHOLOGY OF T HERMAL I NJURY

“ Outliving Cancer provides rare insight into the world of a practicing oncologist who is also an innovative research scientist. I highly recommend it to anyone who wants to know why the official war on cancer has progressed so slowly and how it could be made more effective and humane. Dr. Robert Nagourney is a national treasure and in a sane society would be director of the National Cancer Institute.”
—R ALPH W. M OSS , P H D, A UTHOR , C USTOMIZED C ANCER T REATMENT

“My passion and work for many decades has been in cancer prevention. So it is with great interest that I read Dr. Nagourney’s book, Outliving Cancer . I can see two major advances changing cancer chemotherapy in the next decade: First, we will have personalized testing with individual tumors. Dr. Nagourney is a pioneer in this area, and he tells an interesting story about how he got there and his successes. Second, chemotherapy drugs that only kill tumor cells and have minimal side effects are coming along rapidly. I also see greater understanding and major advances in preventing cancer. Eating a varied diet so that you get your approximately thirty required vitamins and minerals (and, if you are a smoker, giving up smoking) would be a good start on this. In the meantime, we all are grateful to Dr. Nagourney and the other innovators in cancer chemotherapy and cancer prevention.”
—B RUCE N. A MES , P H D, S ENIOR S CIENTIST , C HILDREN’S H OSPITAL O AKLAND R ESEARCH I NSTITUTE (CHORI)

“Dr. Nagourney has earned international recognition as the most prominent leader in the field of chemosensitivity testing. A more primitive proliferative assay led many to reject such testing early on. However, Dr. Nagourney’s pioneering work, based on a highly predictive apoptotic assay, has benefitted innumerable cancer patients and played a pivotal role in their treatment outcomes. I believe all patients deserve the quality of information that Dr. Nagourney’s assay provides, and that in the future, oncology practices will routinely incorporate such testing into the optimal care of patients. I encourage everyone concerned with the treatment of cancer to read Outliving Cancer .”
—K EITH I. B LOCK , MD, M EDICAL D IRECTOR , B LOCK C ENTER FOR I NTEGRATIVE C ANCER T REATMENT ; E DITOR -I N -C HIEF , I NTEGRATIVE C ANCER T HERAPIES , S AGE S CIENCE P RESS ; S CIENTIFIC D IRECTOR , I NSTITUTE FOR I NTEGRATIVE C ANCER R ESEARCH & E DUCATION ; A UTHOR , L IFE O VER C ANCER

“This diary of an oncology physician-scientist is both educational and enjoyable reading for all those interested in cancer and its treatment.”
—P HILIP J. D I S AIA , MD, T HE D OROTHY M ARSH C HAIR IN R EPRODUCTIVE B IOLOGY ; P ROFESSOR , D EPARTMENT OF O BSTETRICS AND G YNECOLOGY , U NIVERSITY OF C ALIFORNIA , I RVINE M EDICAL C ENTER
Outliving Cancer
The Better, Smarter Way to Treat Your Cancer
R OBERT A. N AGOURNEY , MD
The information contained in this book is based upon the research and personal and professional experiences of the author. It is not intended as a substitute for consulting with your physician or other healthcare provider. Any attempt to diagnose and treat an illness should be done under the direction of a healthcare professional. The publisher does not advocate the use of any particular healthcare protocol but believes the information in this book should be available to the public. The publisher and author are not responsible for any adverse effects or consequences resulting from the use of the suggestions, preparations, or procedures discussed in this book.
Should the reader have any questions concerning the appropriateness of any procedures or preparation mentioned, the author and the publisher strongly suggest consulting a professional healthcare advisor.
Basic Health Publications, Inc .
28812 Top of the World Drive
Laguna Beach, CA 92651
949-715-7327 • www.basichealthpub.com
Library of Congress Cataloging-in-Publication Data
Nagournery, Robert A.
Outliving cancer / Robert A. Nagourney, MD.
pages cm
Includes bibliographical references and index.
ISBN 978-1-59120-550-0 (alk. paper)
1. Cancer. 2. Oncology. I. Title.
RC261.N25 2012
616.99’4—dc23
2012045669
Copyright © 2013 by Robert A. Nagourney, M.D.
All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted by any means, electronic, mechanical, photocopying, recording, or otherwise, without written permission from the author.
Editor: Carol Killman Rosenberg • www.carolkillmanrosenberg.com Typesetting/Book design: Gary A. Rosenberg • www.thebookcouple.com Cover design: Dann Froehlich Design
Printed in the United States of America
10  9  8  7  6  5  4  3  2  1
Contents
Acknowledgments
Foreword by Keith I. Block, MD
Preface
Introduction
1.   A Walk in the Park
2.   A Brief History of Chemotherapy and Chemosensitivity Testing
3.   Early Scientific Discoveries
4.   Anything That Works
5.   The Neutrino
6.   Epiphany
7.   Cell Death Allows for Life
8.   Unraveling the Mystery
9.   Finally, Rational Therapy
10.   Never Give Cancer an Even Break
11.   Outliving Hospice
12.   East Meets West
13.   Garlic, Wine, Chocolate, and More
14.   Treatable Cancers Should Be Treated Correctly
15.   When All Else Fails
16.   The Progress in Treating Kidney Cancer
17.   Ah, the Simple Life
18.   What to Do When Your Genes Don’t Fit
19.   Genetic Versus Functional Analysis
20.   Targeted Therapies
21.   The Future of Cancer Research Lies Behind Us
22.   The Causes of Cancer
23.   To Cancer and Beyond
APPENDICES
A.   Cancer Research Explained
B.   What to Expect When You’re Expecting a Conversation with Your Oncologist
C.   A Practical Guide for the Use of Chemosensitivity Testing
D.   Assay Criteria
E.   Physician/Patient Advocate Resources
Glossary
References
About the Author
Acknowledgments
I start by thanking Phil Schein, MD, who took me under his wing and guided me through my first experiences with peer-reviewed publications in oncology.
I would also like to thank Larry Weisenthal, MD, PhD, for introducing me to the laboratory technology that has influenced every aspect of my work in oncology.
A very special thanks to Dr. Sheldon Hendler for years of collaboration and brilliant scientific discussion.
Gale (Morrie) Granger for productive collaborations and my introduction to the molecular biology of the human immune system. Kenneth Tew, PhD, who provided me laboratory space and technical support during my fellowship, enabling me to begin my first drug sensitivity lab.
Philip Di Saia, MD, for his support and assistance over the years.
I would like to thank the many surgeons who have collaborated with us to provide tissue samples for our analysis, with particular thanks to Drs. Robert Shuman, Kent Azaren, Imad Shbeeb, Tomi Evans, Anton Bilchik, Peter Dottino, Helmut Schellhas, Sean Cao, Philip Boudreaux, Eugene Woltering, Robert Barone, and Paul Sugarbaker.
I thank Drs. Mel Hoshiko, Joanne Rutgers, Gloria Bertucci, Lowell Rogers, Milton Drachenberg, Julio Ibarra, Steven Romansky, Emanuel Ferro, Joyce King, Lisa Shane, and Savita Ries, as well as all the members of the Long Beach Memorial Medical Center Pathology Department for their expert assistance in processing tissue samples.
Also, my appreciation to my clinical oncology colleagues, Drs. William Lyons, Jonathan Blitzer, Eknath Deo, Nilesh Vora, John Link, Thomas Asciuto, and Steven Lake, as well as my radiation oncology colleagues, Drs. A. M. Nisar Syed, Ajmel A. Puthawala, and Stephen Doggett for their participation and support in our clinical investigations.
I would especially like to thank my laboratory staff, Steven Evans, Paula Bernard, Eric Federico, and all the past members of our group for overseeing the quality of our operations and dedication to our patients. As well as Shari Burt and Robyn LaFrance for their dedication, perseverance, and multiple abilities.
I’d like to thank Marylyn Paulsen, Tonja Smith, and Debbie Fridman for their hard work in our clinical research department and Cathy Kopy for her continued support.
I also want to thank Loretta Sta