The Complete Book of Ketones
245 pages
English

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245 pages
English

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Comprehensive Guide: More than just a “diet” book, it’s the first and only comprehensive guide to everything keto, and includes strategies for increasing ketone levels, an overview of the different types of ketogenic diets and their benefits, a list of ketone supplements, keto-friendly recipes and ingredients, sources for finding specialty foods, and much more.


The Keto Craze: Interest in the Keto diet has reached its peak popularity, and it doesn’t look like it’s going away anytime soon. Keto transformation stories, keto recipes and #keto are all over social media and trending features in lifestyle and health magazines across the nation. This book breaks down the why behind the results, and cuts through the confusion floating around online.


Ketone Expert: Dr. Mary Newport is a leader in her field, and the first to link ketones to Alzheimer’s disease in her previous work Alzheimer’s Disease: What if There Was a Cure?: The Story of Ketones.


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Publié par
Date de parution 26 février 2019
Nombre de lectures 0
EAN13 9781684421626
Langue English
Poids de l'ouvrage 2 Mo

Informations légales : prix de location à la page 0,1200€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

Extrait

THE COMPLETE BOOK OF KETONES
A Practical Guide to Ketogenic Diets and Ketone Supplements
by MARY T. NEWPORT, M.D.
Foreword by Theodore VanItallie, M.D.
Graphics by Joanna Newport Rand
TURNER PUBLISHING COMPANY
Turner Publishing Company
Nashville, Tennessee
www.turnerpublishing.com
Copyright 2019 Mary Newport
The Complete Book of Ketones: A Practical Guide to Ketogenic Diets and Ketone Supplements
No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Sections 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 750-4744. Requests to the Publisher for permission should be addressed to Turner Publishing Company, 4507 Charlotte Avenue, Suite 100, Nashville, Tennessee, (615) 255-2665, fax (615) 255-5081, E-mail: submissions@turnerpublishing.com .
Limit of Liability/Disclaimer of Warranty: While the publisher and the author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor the author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.
Cover design: Maddie Cothren
Book design: Tim Holtz
Library of Congress Cataloging-in-Publication Data Upon Request
9781684421602 Paperback
9781684421619 Hardback
9781684421626 eBook
Printed in the United States of America
18 19 20 10 9 8 7 6 5 4 3 2 1
DEDICATION
This is dedicated to the memory of Steven Jerry Newport, my best friend and husband of forty-three years, who made it possible for me to be both a mother and a doctor. He said taking care of our girls was the best job he ever had. He was an active, intelligent, and creative person, helpful in every way to everyone, and one of the most pleasant people you could ever meet. He was well aware of the toll Alzheimer s disease was taking on him and fully embraced the idea of ketones as an alternative fuel for the brain. He was a willing and eager participant in his reprieve from the disease, first by taking ketogenic medium-chain triglycerides and coconut oil, then a ketone ester in a pilot study of one patient. We were given at least three extra good years with Steve, thanks to ketogenic therapies.
Steve lost his battle with Alzheimer s disease and Lewy body dementia on January 2, 2016. This book represents his legacy to the world.

Steven Jerry Newport-1950 to 2016.
CONTENTS
Foreword by Theodore VanItallie, MD
Acknowledgements
Introduction: Steve s Emergence from Alzheimer s Awakens a Messenger for Ketones in Me
1. Why Go Keto?
2. Quick Start to a Low-Carb Ketogenic Diet
3. Ketones as a Primitive Fuel: Little Molecule, Big Effects
4. The Ketogenic Lifestyle: Evolution and Historical Perspectives
5. Pioneers and Rising Stars in Ketone Research and Practice: A Historical Review
6. The Full Spectrum of Ketogenic Diets
7. Other Strategies to Help You Go Keto
8. Considerations for Special Populations: Moms, Children, Seniors, People with Cancer or Other Medical Conditions, and Pets
9. Monitoring for Healthy and Not-So-Healthy People
10. Common and Not-So-Common Problems with Exogenous Ketones and the Ketogenic Diet
11. The Controversy About Saturated Fat, Cholesterol, and Your Heart
12. The Question: Why Go Keto? The Answer: Why Not?
Addendum: Questions and Answers About Coconut Oil, MCT Oil, and Exogenous Ketone Supplements
References by Chapter
Keto Friendly Recipes
Resources
Index
About the Author
FOREWORD
Dr. Mary T. Newport, author of this invaluable compilation of up-to-date information about ketogenic diets and supplements, could not have foreseen how seriously her life would be affected by her untimely confrontation with a wholly unexpected adversary-Alzheimer s disease-induced dementia (ADd). In the space of a few months, her existence as a busy neonatologist and homemaker was transformed. And in the subsequent course of her courageous campaign against this implacable neurodegenerative disorder, she became a model of initiative and perseverance. These qualities were her strongest weapons in the fight to save her beloved husband, Steve, from rapidly evolving dementia. During this protracted battle, she found a treatment approach-not a cure-that worked surprisingly well for Steve for almost four years.
Sadly, misfortune challenged her at a time when she should have been allowed to continue to enjoy her marriage to Steve unimpeded. It was his generosity of spirit that enabled her to attend medical school, while he was content to stay at home and care for their young children.
But fate intervened. In 2001, at age 51, Steve Newport, in the midst of a promising career as an accountant, developed early-onset dementia (which post-mortem studies disclosed was caused by a virulent combination of Alzheimer s disease with a condition known as Lewy body dementia). Deterioration of his memory and cognitive skills progressed with alarming speed, and by 2006 he was unable to function in his job and had to give up driving. As his illness continued to progress, he became progressively more confused and disoriented and eventually was unable to carry out simple household chores or self-care without assistance.
The collective experience and professional knowledge of Mary s Newport s medical colleagues had no promising treatments to suggest. Steve s situation soon reached a point where most spouses would have thrown up their hands and accepted palliative care as the only humane intervention possible.
But surrender is not in Mary Newport s lexicon. By will alone, she forced herself to conduct a systematic search of the medical literature, hunting for any evidence of a treatment approach that might counter the process that was inexorably destroying brain functions that had made Steve such an admirable human being. As her mission progressed, Mary found her first glimmer of hope in the writings of Dr. Richard L. Veech, a Harvard Medical School graduate who went on to take graduate training in biochemistry at Britain s University of Oxford. There Veech earned the doctor of philosophy degree (DPhil) for studies carried out under the tutelage of Sir Hans Krebs, discoverer of the famed Krebs cycle. After Oxford, Veech joined the intramural research staff at the National Institutes of Health and founded the Laboratory of Metabolic Control, which, at age eighty-two, he still heads.
Krebs had an interest in ketone body metabolism, which was transmitted to Veech. But the principal ketone bodies, D betahydroxybutyrate ( D - OHB) and acetoacetate (AcAc) did not come into their own scientifically until 1966-67. That s when a group of clinical scientists working under the leadership of Dr. George F. Cahill Jr. at Harvard s Peter Bent Brigham Hospital discovered the importance of ketone bodies for brain function and human survival. These investigators found that, contrary to the belief of earlier scientists, the ketones produced in abundance by the liver during fasting are far from being potentially dangerous waste by-products of a starving organism. Rather, they serve as the brain s primary alternative fuel when its usual fuel, glucose, is in short supply. Unlike the fatty acids from which they are derived, ketone bodies can cross the blood-brain barrier (BBB), after which they are readily metabolized by the brain s parenchymal cells and neuronal structures.
The extra ketones manufactured during periods of starvation have been found to alleviate the brain s destructive dependence on glucose derived from the breakdown of the body s stores of essential protein. Thus, it gradually became clear to knowledgeable scientists that the ketone body safety net is the outcome of an evolutionarily determined adaptation designed to prolong and save the lives of starving mammals, humans included. As a result of the original observations by Cahill and his co-workers, ketone bodies, derived from the body s fat stores, became recognized as a life-prolonging and lifesaving fuel for individuals whose sources of dietary energy were cut off by famine or other interruptions, including politically- or religiously-motivated fasting.
As a consequence of her desperate literature search, Dr. Newport came across several articles that gave reason to hope that placing Steve on a ketogenic diet and/or feeding him coconut oil-derived medium-chain triglyceride (MCT) supplements known to raise blood ketone levels to a modest degree would provide his brain with sufficient energy from D - OHB and AcAc to rescue his failing brain function. Although the precise reason why this approach is often effective is not entirely clear, the rationale for trying it is scientifically sound. As reported by Stephen Cunnane and his co-workers at the University of Sherbrooke in Quebec, as well as by several other investigators, incontrovertible evidence exists that, in general, elderly individuals and patients with classical late onset Alzheimer s dementia are unable to use the brain s normal fuel, glucose, with normal efficiency. This reduction in brain glucose uptake is thought to give rise to hypometabolism (reflecting a degree of energy shortage) occurring in brain structures inv

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