Towards the identification of regulatory networks using statistical and information theoretical methods on the mammalian transcriptome [Elektronische Ressource] / vorgelegt von Dominik Ralph Lionel Lutter

Towards the identi cation of regulatory networksusing statistical and information theoreticalmethods on the mammalian transcriptomeDissertation zur Erlangung des Doktorgrades der Naturwissenschaften(Dr. rer. nat.) der Fakultat III { Biologie und Vorklinische Medizin der UniversitatRegensburgvorgelegt vonDominik Ralph Lionel Lutter aus NairobiApril 20092Das Promotionsgesuch wurde eingereicht am: 3.06.2009.Die mundlic he Prufung fand am 9.11.2009 statt.Die Arbeit wurde angeleitet von Prof. Dr. Elmar W. Lang.Prufungsaussc hu :Prof. Dr. Dr. Hans R. Kalbitzer (Vorsitzender)Prof. Dr. Elmar W. Lang (1. Gutachter)Prof. Dr. Dr. Fabian J. Theis (2.hter)Prof. Dr. Reinhard Sterner (Weiterer Prufer)4‘Just look down there’ said Denny.‘That seemingly endless convoy,trailing along the dried up valley below,look for all the world like ants.’‘They ARE ants’ said his companion Minnie,‘And so are we’.And it was true.They were both ants,perched on the edge of a clod of earthno more than six inches high.‘Oh’, sighed Denny sadly,‘I forgot’.Robert Wyatt { Comicopera56SummaryAll life known consists of cells. Every cell contains DNA. DNA is just a code. Acode existent of four simple letters A, T, G and C. But the sequence composed ofthese letters contains nearly all information needed to form a complete organismas complex as a human being out of a single fertilized egg cell.