Time-resolved quantifikation of centrosomes by automated image analysis suggests limiting component to set centrosome size in C. elegans embryos [Elektronische Ressource] / eingereicht von Steffen Jaensch

T I M E - R E S O LV E D Q U A N T I F I C AT I O N O F C E N T R O S O M E SB Y A U T O M AT E D I M A G E A N A LY S I SS U G G E S T S L I M I T I N G C O M P O N E N TT O S E T C E N T R O S O M E S I Z E I N C . E L E G A N S E M B RY O SdissertationS T E F F E N J A E N S C HiiT I M E - R E S O LV E D Q U A N T I F I C AT I O N O F C E N T R O S O M E SB Y A U T O M AT E D I M A G E A N A LY S I SS U G G E S T S L I M I T I N G C O M P O N E N TT O S E T C E N T R O S O M E S I Z E I N C . E L E G A N S E M B RY O Sdissertationzur Erlangung des akademischen Grades Doktor rerum naturalium (Dr. rer. nat.)vorgelegt an derTechnischen Universität DresdenFakultät Informatikeingereicht vonDiplom-Informatiker Steffen Jaenschgeboren am 21. Juni 1980 in RüdersdorfGutachter: Prof. Dr. Michael Schroeder (TU Dresden, Fakultät Informatik)Dr. Eugene W. Myers (Janelia Farm Research Campus, USA)Tag der Verteidigung: 02. Dezember 2010Dresden im September 2010Steffen Jaensch: Time-Resolved Quantification of Centrosomes by Automated ImageAnalysis Suggests Limiting Component to Set Centrosome Size in C. Elegans Em-bryos, Dissertation, September 2010To my familyviA B S T R A C TThe centrosome is a dynamic organelle found in all animal cells that serves asa microtubule organizing center during cell division.