The role of fat cell apoptosis during obesity-associated adipose tissue inflammation [Elektronische Ressource] / Michaela Keuper

DissertationMichaela KeuperUlm UniversityThe role of fat cell apoptosis during obesity-associated adipose tissue inflammation2011The role of fat cell apoptosis during obesity-associated adipose tissue inflammation Dissertationzur Erlangung des Doktorgrades Dr. rer. nat. der Fakultät für Naturwissenschaften der Universität Ulmvorgelegt von Michaela Keuper aus Hilden Ulm 2011 Prof. Dr. Axel GroßAmtierender Dekan: _________________________________Prof. Dr. Klaus-Dieter Spindler1. Gutachter: PD Dr. Frank Rosenau2. Gutachter: _________________________________Prof. Dr. Martin WabitschWeitere Gutachter: 07.11.2011Tag der Promotion: _________________________________CONTENTS The work for this PhD-thesis was carried out in the Division of Pediatric Endocrinology and Diabetology Department of Pediatrics and Adolescent Medicine Ulm University and it is based on the following publication: Keuper, M. et al. An inflammatory micro-environment promotes human adipocyte apoptosis. Mol. Cell. Endocrinol 339, 105-113 (2011) CONTENTSContentsAbbreviations ....................................................................................................... iv1 Introduction.................................................................................................... 11.1 Obesity.................................................................................