The gene region UL128-UL131A of human cytomegalovirus (HCMV) is essential for monocyte infection and block of migration [Elektronische Ressource] : characterisation of the infection of primary human monocytes / presented by Sarah Straschewski

Ulm University Hospital Institute of Virology Director: Prof. Dr. med. Thomas Mertens The gene region UL128-UL131A of human cytomegalovirus (HCMV) is essential for monocyte infection and block of migration Characterisation of the infection of primary human monocytes Dissertation to obtain the Doctoral Degree of Human Biology (Dr. biol. hum.) at the Faculty of Medicine, University of Ulm presented by Sarah Straschewski from Ulm 2010 Dean of the Faculty: Prof. Dr. rer. nat. Thomas Wirth 1. Reviewer: Prof. Dr. med. Thomas Mertens 2. Reviewer: Prof. Dr. rer. nat. Klaus-Dieter Spindler Day doctorate awarded: 18.2.2011 II To Giada my parents and Bernd You are my towers of strength III Index 1. Introduction ................................................................................................. 1 1.1 The History of cytomegalovirus ............................................................................... 1 1.2 The family of Herpesviruses ..................................................................................... 1 1.3 The human cytomegalovirus .................................................................................... 2 1.4 Monocytes...................................................................................................................