The C. elegans p53 pathway [Elektronische Ressource] / vorgelegt von Björn Schumacher

The C. elegans p53 pathway Dissertation der Fakultät für Biologie der Ludwig-Maximilians-Universität München vorgelegt von Björn Schumacher München 2003 Erstgutachter: Prof. Dr. Erich Nigg Zweitgutachter: Prof. Dr. Charles David Tag der mündlichen Prüfung: 29. März 2004 Table of content Table of content .................................................................................................................. 1 Statement............................................................................................................................. 3 Abstract.............................................................................................................................. 4 List of abbreviations ........................................................................................................... 5 1 Introduction............................................................................................................... 6 1.1 Programmed cell death ....................................................................................... 6 1.2 ed cell death in C. elegans ................................................................. 8 1.3 DNA damage induced apoptosis....................................................................... 21 1.4 p53..................................................................................................................... 27 1.5 BH3 only proteins in apoptosis..........