The AVP deficit in LAB mice [Elektronische Ressource] : physiological and behavioral effects / vorgelegt von Melanie Keßler

The AVP Deficit in LAB Mice: Physiological and Behavioral Effects Dissertation der Fakultät für Biologie der Ludwig-Maximilians-Universität München vorgelegt von Melanie Keßler am 26. Oktober 2006 1. Gutachter: Prof. R. Landgraf 2. Gutachter: Prof. G. Schuller Tag der mündlichen Prüfung: 14. Februar 2007 The AVP Deficit in LAB Mice: Physiological and Behavioral Effects Dissertation Faculty of Biology Ludwig Maximilians University Munich submitted by Melanie Keßler October 26, 2006 Table of Contents Table of Contents Brief Description 1 Introduction ..........................................................................................................1 1.1 Neuroendocrine Background of the Stress Response ..................................3 1.2 Biological Bases and Pharmacological Treatment of Anxiety and Affective Disorders .................................................................................................................7 1.3 Animal Models of Anxiety and Affective Disorders......................................10 1.4 Arginine-Vasopressin..................................................................................13 1.5 Pre- and Postnatal Influences on Stress-related Behavior..........................17 1.6 Scope of the Thesis .............................................................