Targeting MAPK signaling in melanoma cells [Elektronische Ressource] : implications for immune recognition and cell fate / presented by Stefan Maßen

Targeting MAPK Signaling in Melanoma Cells - Implications for Immune Recognition and Cell Fate Referees: Prof. Dr. Stephan Urban PD Dr. Christine S. Falk Dissertation submitted to the combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences presented by Diplom-Biologe Stefan Maßen born in: Freiburg im Breisgau Oral examination: …………… Table of contents Table of contents Table of contents .......................................................................................................................... 5 Summary ....................................................................................................................................... 7 Zusammenfassung ....................................................................................................................... 8 I.  Introduction ........................................................................................................................... 9 I.1  Melanoma ............................................................................................................................. 10 I.1.1  Oncogenic MAPK signaling ............................................................................................... 10 I.1.2  MAPK mutations in melanoma ............