Targeting insulin-like growth factor-I receptor in breast cancer [Elektronische Ressource] / Beate Christiane Litzenburger

Targeting Insulin-like Growth Factor - I Receptor in Breast Cancer Beate Christiane Litzenburger 1 2 Targeting Insulin-like Growth Factor - I Receptor in Breast Cancer Von der Fakultät für Mathematik, Informatik und Naturwissenschaften der RWTH Aachen University zur Erlangung des akademischen Grades einer Doktorin der Naturwissenschaften genehmigte Dissertation vorgelegt von Diplom-Biologin Beate Christiane Litzenburger aus Hattingen Berichter: Universitätsprofessor Dr. Bernhard Lüscher essor Dr. Lothar Elling Tag der mündlichen Prüfung: 28.06.2010 Diese Dissertation ist auf den Internetseiten der Hochschulbibliothek online verfügbar. 3 4 Acknowledgments Acknowledgments I would like to take this opportunity to acknowledge and thank a number of people for their support throughout the process of my dissertation. First and foremost, I would like to acknowledge my mentor and advisor Professor Dr. Adrian V. Lee at Baylor College of Medicine for making this study possible. His steadfast support and encouragement over the years, trust and dedication has been truly a source of learning and inspiration throughout my training. He was always willing to devote his time and energy to encourage and mentor me. He has shown me to work on challenging problems and not to give up.