Synthesis of novel functional poly(1,4-ketone)s bearing pendant bioactive moieties [Elektronische Ressource] : an approach to design biocompatible materials / vorgelegt von Violeta Malinova

Synthesis of Novel Functional Poly(1,4-ketone)s Bearing Pendant Bioactive Moieties: An Approach to Design Biocompatible Materials Dissertation zur Erlangung des Doktorgrades Dr. rer. nat. der Fakultät für Naturwissenschaften der Universität Ulm vorgelegt von Violeta Malinova aus Dupnitza/Bulgarien 2006 Amtierender Dekan: Prof. Dr. K.-D. Spindler 1. Gutachter: Prof. Dr. B. Rieger 2. Gutachter: Prof. Dr. D. Volkmer Tag der Promotion: 29.05.2006 Contents Chapter 1. General Introduction………………………………………………………………. 1 Chapter 2. Polymers from Carbon Monoxide and α-Olefins ……………………………..… 7 2.1 Polyketones - highly attractive materials…………………………………………………… 7 2.2 Synthesis of polyketones - historical overview…………………………………………….. 8 2.3 Mechanism of polyketone formation………………………………………………………... 9 2.4 Structural diversity of polyketones………………………………………………………….. 16 2.5 Copolymers of CO and functional α-olefins ………………………………………………… 17 2.6 Terpolymers of CO, functional and non-functional α-olefins……………………………….. 20 2.7 References……………………………………………………………………………………. 22 Chapter 3. Functionalization of Propylene/CO with Bioactive Molecules via Derivatization Reactions ……………………………..………………………………………... 25 3.1 Functionalization of polymers by chemical modification……………………………………. 25 3.2 Chemical modifications of polyketones……………………………………………………… 27 3.3 Reduction of polyketones…………………………………………………………………….. 29 3.