Synthesis and studies of annelated quinolizinium derivatives as versatile constructs for fluorescent probes and ligands for triple helical and abasic DNA structures [Elektronische Ressource] / vorgelegt von Anton Granzhan

Synthesis and Studies of Annelated Quinolizinium Derivatives as Versatile Constructs for Fluorescent Probes and Ligands for Triple-Helical and Abasic DNA Structures DISSERTATION zur Erlangung des naturwissenschaftlichen Doktorgrades vorgelegt von Anton Granzhan geb. am 14. Oktober 1979 in Rubishne (Ukraine) eingereicht beim Fachbereich 8 (Chemie–Biologie) der Universität Siegen Siegen 2006 urn:nbn:de:hbz:467-2403 Eingereicht am: 14. Juni 2006 beim Fachbereich 8 (Chemie–Biologie) 1. Gutachter: Univ.-Prof. Dr. Heiko Ihmels 2. Gutachter: Univ.-Prof. Dr. Michael Schmittel der Dissertation 1. Prüfer: Univ.-Prof. Dr. Heiko Ihmels 2. Prüfer: Univ.-Prof. Dr. Michael Schmittel 3. Prüfer: Univ.-Prof. Dr. Alf Mews des öffentlichen Promotionskolloquiums Tag des öffentlichen Promotionskolloquiums: 18. August 2006 Doktorurkunde ausgehändigt am: Le hasard ne favorise que les esprits prepares. Louis Pateur Моїм батькам присвячую ACKNOWLEDGEMENTS I am first and foremost thankful to Professor Dr. Heiko Ihmels for giving me an opportunity to work in his group in the stimulating atmosphere of motivation and creativity, and especially for giving generous support to all my ideas. I would like to particularly acknowledge his rapid corrections of this work and other manuscripts. I am immensely indebted to Dr. Yuri Slominskii and Dr.