Synthesis and characterization of photoswitchable building blocks based on spirobenzopyrans and new approaches for postsynthetic oligonucleotide labeling [Elektronische Ressource] / vorgelegt von Christoph Beyer

Synthesis and characterization of photoswitchable building blocks based on spirobenzopyrans and new approaches for postsynthetic oligonucleotide labeling Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften (Dr. rer. nat.) an der Naturwissenschaftlichen Fakultät IV - Chemie und Pharmazie - der Universität Regensburg vorgelegt von Christoph Beyer aus Freihung Regensburg, 2010 The experimental part of this work was carried out between February 2006 and March 2010 under the supervision of Prof. Dr. Hans-Achim Wagenknecht at the Institute of Organic Chemistry, University of Regensburg, Regensburg/Germany. The PhD thesis was submitted on: 09.06.2010 The colloquium took place on: 06.07.2010 Board of Examiners: Prof. Dr. Joachim Wegener (Chairman) st Prof. Dr. Hans-Achim Wagenknecht (1 Referee) nd Prof. Dr. Burkhard König (2 Referee) Prof. Dr. Otto S. Wolfbeis (Examiner) Acknowledgements First, I gratefully and sincerely thank my supervisor Prof. Dr. Hans-Achim Wagenknecht for his constant encouragement and excellent support. He was always there to listen and to give advice, to ask me good and helpful questions and discuss ideas. It was under his guidance that I gained so much drive to tackle things head on and I thank him for the granted scientific freedoms. I also thank the members of my thesis committee, Prof. Dr. Burkhard König, Prof. Dr. Otto S.