Synaptic plasticity in mature cultured hippocampal entorhinal cortex slices: activity-dependent regulation of cAMP response element binding protein [Elektronische Ressource] / von Jill K. Leutgeb, Howard

Synaptic Plasticity in Mature Cultured Hippocampal-Entorhinal Cortex Slices: Activity-Dependent Regulation of cAMP Response-Element Binding Protein D i s s e r t a t i o n zur Erlangung des akademischen Grades doctor rerum naturalium (Dr. rer. nat.), genehmigt durch die Fakultät für Naturwissenschaften der Otto-von-Guericke-Universität Magdeburg von M.Sc. Jill K. Leutgeb/ Howard geb. am 11. März 1974 in Provo, Utah, USA Gutachter: Prof. Dr. Julietta U. Frey Prof. Dr. Denise Managhan-Vaughan Prof. Dr. Herbert Schwegler Eingereicht am: 28. Oktober 2003 Verteidigung am: 26. April 2004 To Stefan 1 ACKNOWLEDGEMENTS I would like to thank Prof. Dr. Julietta U. Frey for her support in this research, for providing me with the scientific freedom and means necessary to expand my scientific goals and interests, as well as in allowing flexibility for the completion of this work. I would also like to thank the members of the Neurophysiology Department, for their help and friendship throughout my studies, particularly my colleague and mentor Dr. Thomas Behnisch. I would also like to thank my family for their support and encouragement throughout the multiple phases of my education, and for helping me realize there are no limitations to what I can accomplish. I give special thanks namely to Stefan.