Supramolecular structures of dendronized polymers and DNA on solid substrates [Elektronische Ressource] / von Illdiko Maria Gössl

Supramolecular structures of dendronizedpolymers and DNA on solid substratesD I S S E R T A T I O Nzur Erlangung des akademischen Gradesdoctor rerum naturalium(Dr. rer. nat.)im Fach Physikeingereicht an derMathematisch-Naturwissenschaftlichen Fakultat¨ IHumboldt-Universit¨at zu BerlinvonFrau Dipl.-Phys. Illdiko Maria G¨osslgeboren am 03.02.1974 in KasselPr¨asident der Humboldt-Universit¨at zu Berlin:Prof. Dr. Jur¨ gen MlynekDekan der Mathematisch-Naturwissenschaftlichen Fakult¨at I:Prof. Dr. Michael LinscheidGutachter:1. Prof. Dr. J. P. Rabe2. Prof. Dr. B. R¨oder3. Prof. Dr. R. R. Netzeingereicht am: 15.4.2003Tag der mundlic¨ hen Prufung:¨ 30.6.2003AbstractComplexes of oppositely charged polyelectrolytes play an important role inboth biology and material science, for instance DNA condensation in vitro,nucleosomal structure, non-viral gene transfection systems as well as layer-by-layer adsorption. Although there are theories predicting overcharging of poly-electrolyte complexes, the driving forces are still under debate and systematicexperimental studies on single polyelectrolytes remain challenging. Thereforethe question arose if it is possible to analyze single polyelectrolyte complexes,using DNA and dendronized polymers, with the scanning force microscope inorder to investigate the complexation in detail.