Studying the L- and M-cone ratios by the multifocal visual evoked potential [Elektronische Ressource] / vorgelegt von Alice Lap-Ho Yu

Aus der Universitäts-Augenklinik Tübingen Abteilung Augenheilkunde II Ärztlicher Direktor: Professor Dr. E. Zrenner Studying the L- and M-cone ratios by the multifocal visual evoked potential Inaugural-Dissertation zur Erlangung des Doktorgrades der Medizin der Medizinische Fakultät der Eberhard-Karls-Universität zu Tübingen vorgelegt von Alice Lap-Ho Yu aus Hongkong 2005 Dekan: Professor Dr. C. D. Claussen 1. Berichterstatter: Professor Dr. E. Zrenner 2. Berichterstatter: Professor Dr. H. – P. Thier To my parents TABLE OF CONTENTS 1 Introduction 1 1.1 Physiology of Color Vision 3 1.1.1 Morphology of Cones 3 1.1.2 Spatial Distribution of Cones 4 1.1.3 Processing of Visual Signals in the Retina 4 1.1.4 Ganglion Cells and the MC and PC Pathways 6 1.1.5 Red-green and Luminance Pathways 8 1.2 Significance of the Relative Number of L- and M-cones 10 1.3 Multifocal Visual Evoked Potential (mfVEP) 12 1.4 Multifocal Stimulation 13 1.5 Silent Substitution Technique 14 1.6 Thesis Goals 15 2 Materials and Methods 16 2.