Structure and function of supercomplexes in photosynthetic and respiratory membranes of eukaryotes [Elektronische Ressource] / von Jesco Heinemeyer

Structure and function of supercomplexes in photosynthetic and respiratory membranes of eukaryotes Von der Naturwissenschaftlichen Fakultät der Gottfried Wilhelm Leibniz Universität Hannover zur Erlangung des Grades Doktor der Naturwissenschaften Dr. rer. nat. genehmigte Dissertation von Dipl.-Biol. Jesco Heinemeyer geboren am 12. Juni 1976 in Hildesheim 2007 Referent: Prof. Dr. Hans-Peter Braun Koreferent: Prof. Dr. Udo Schmitz Tag der Promotion: 11.07.2007 Abstract During the last few years many reports on the supramolecular organization of the oxidative phophorylation (OXPHOS) system and photophosphorylation (PHOTPHOS) system have been published. In both fields of research many supercomplexes with specific compositions for a number of organisms were described. Interestingly, in the past OXPHOS research was mainly based on Blue-native polyacrylamide gel electrophoresis (BN-PAGE) while PHOTPHOS research often used electron microscopy (EM) in combination with single parti-cle analysis. By transferring EM in combination with single particle analysis onto the field of OXPHOS research this thesis provides new results on the supramolecular structure of dimeric ATP syn-thase of Polytomella mitochondria.