Roles of Msb2p and other putative sensors in environmental responses of Candida albicans [Elektronische Ressource] / presented by Fabien Cottier

Roles of Msb2p and other putative sensors in environmental responses of Candida albicans Inaugural - Dissertation Presented by Fabien COTTIER From Lyon, France Submitted to attain the doctoral degree of the Mathematisch-Naturwissenschaftlichen Fakultät der Heinrich-Heine-Universität Düsseldorf DÜSSELDORF December 2007 Referee: Prof. Dr. J.F. Ernst Co-referee: Prof. Dr. K. Jäger müdlichen Prüfung: 18.01.2008 i 1. Introduction ............................................................................................................................ 1 1.1 Candida albicans: friend and foe...................................................................................... 1 1.2 Dimorphism: from yeast to hyphae.................................................................................. 2 1.2.1 MAPK cascade pathways.......................................................................................... 2 1.2.2 cAMP-PKA pathway................................................................................................. 3 1.2.3 Other pathways.......................................................................................................... 5 1.3 Sensing the environment .................................................................................................. 5 1.3.1 Pheromones ....