Roles of HMG-box transcription factors in the pancreas development of the mouse (mus musculus, Linnaeus, 1758) [Elektronische Ressource] / vorgelegt von Oleg Lioubinski

Roles of HMG-box Transcription Factorsin the Pancreas Development of the Mouse(mus musculus, Linnaeus, 1758)Dissertationzur Erlangung des Doktorgradesdes Fachbereiches Biologieder Universität Hamburgvorgelegt vonOleg Lioubinskiaus Novosibirsk, RusslandHamburg, April 2004Table of ContentsSUMMARY...................................................................................................................................................1I INTRODUCTION...............................................................................................................................41.1 TRANSCRIPTION FACTORS........................................................................................................... 41.1.1 Eukaryotic Gene, Regulation of Transcription ...................................................................... 41.1.2 Transcription Factors.............................................................................................................. 51.2 STRUCTURE, EXPRESSION AND KNOWN DEVELOPMENTAL ROLES OF THE HMG BOXTRANSCRIPTION FACTORS IN MAMMALS................................................................................................. 61.2.1 SOX Transcription Factors.... 61.2.1.1 Expression and Functions of Sox Transcription Factors in Mammalian EmbryonicDevelopment..................................................................................................................................... 81.2.