Role of Wnt/GSK3β/β-catenin [Wnt-GSK3-beta-beta-catenin] signaling pathway in cardiac and pulmonary vascular remodeling [Elektronische Ressource] / by Sklepkiewicz, Piotr Lukasz

Role of Wnt/GSK3β/β-catenin signaling pathway in cardiac and pulmonary vascular remodeling Inaugural Dissertation submitted to the Faculty of Medicine in partial fulfillment of the requirements for the PhD-Degree of the Faculties of Veterinary Medicine and Medicine of the Justus Liebig University Giessen by Sklepkiewicz, Piotr Lukasz of Torun, Poland Giessen 2010 From the Department of Medicine Director / Chairman: Prof. Dr. Werner Seeger of Medicine of the Justus Liebig University Giessen First Supervisor and Committee Member: Prof. Ralph Theo Schermuly, PhD Second Supervisor and Committee Member: Prof. Jeanine D‟Armiento, MD, PhD Committee Members: Date of Doctoral Defense: I Table of Content Table of Content ............................................................................................................................. I List of Figures: IV List of Tables: .............................. VI List of Abreviations: .................................................................................................................. VII 1. Introduction ........................... 1 1.1. Pulmonary Hypertension..........................................................................................................1 1.1.1. Definition and research history of Pulmonary Hypertension ............................. 1 1.1.2. Classification of Pulmonary Hypertension .........