Role of the protein Sus1 and its interaction with the Sac3_1hnC_1hnI_1hnD motif in transcription-coupled mRNA export [Elektronische Ressource] / presented by Christoph Klöckner

Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences presented by Diplom-Biologe Christoph Klöckner born in: Bonn, Germany Oral examination: ........................... Role of the protein Sus1 and its interaction with the CIDSac3 motif in transcription-coupled mRNA export Referees: Prof. Dr. Eduard Hurt Dr. Oliver Gruss DECLARATION I hereby declare that I have written the submitted dissertation myself and in this process have used no other sources or materials than those expressly indicated. December 17, 2009 __________________________________ (Christoph Klöckner) Acknowledgements ACKNOWLEDGEMENTS I would like to thank Professor Dr. Ed Hurt for the opportunity to do my PhD thesis in his lab and for his scientific guidance and continuous support for this project during my PhD research. In addition, I want to thank Dr. Oliver Gruss for being the second referee of this thesis and for his feedback and helpful comments throughout my PhD as a member of the thesis advisory committee. I want to express my gratitude to Alwin Köhler who was a great scientific counsellor during the last years of my PhD thesis.