Role of the oligodendrocytic connexin47 in CNS myelination [Elektronische Ressource] / von Marta Maglione

Aus dem Max-Delbrück-Centrum für Molekulare Medizin DISSERTATION Role of the oligodendrocytic connexin47 in CNS myelination zur Erlangung des akademischen Grades Doctor of Philosophy in Medical Neurosciences (PhD in Medical Neuroscience) vorgelegt der Medizinischen Fakultät Charité – Universitätsmedizin Berlin von Marta Maglione aus Genoa, Italien Oligodendrocytic coupling in CNS white matter ii Gutachter: 1. Prof. Dr. H. Kettenmann 2. Prof. Dr. K.-A. Nave 3. Prof. Dr. med. R. Dermietzel Datum der Promotion: 18.10.2010 Oligodendrocytic coupling in CNS white matter iiiAcknowledgments I sincerely thank Prof. Dr. H. Kettenmann for giving me the opportunity to work at this project and for his supervision, in particular for making me grow as a scientist; Prof. Dr. K. Willecke for his precious contribution to a project which was originally born from an idea of Dr. B. Uhlenberg; and my special friend and previous collegue Dr. B. Haas for her unique supervision when I moved my first steps in the lab, for her help along the past years and for her friendship; last but not least for carefully proof reading this thesis. I thank my great collaborator Oliver Tress, who generated the Cx47M282T mutant mice, for all the motivating scientific (and not) discussions along the way.