Regulation of hepatitis C virus translation by the viral internal ribosome entry site and the 3'-untranslated region [Elektronische Ressource] / vorgelegt von Yutong Song

Inauguraldissertation zur Erlangung der Doktorwürde der Naturwissenschaftlichen Fachbereiche Biologie, Chemie und Geowissenschaften im Fachbereich Biologie der Justus-Liebig-Universität Giessen Vorgelegt von Yutong Song M.Sc.-Virology Biochemisches Institut der Medizinischen Fakultät der Justus-Liebig-Universität Giessen Giessen, Januar 2006 Regulation of Hepatitis C Virus translation by the viral internal ribosome entry site and the 3´-untranslated region Supervisors: Prof. Dr. Albrecht Bindereif Institute of Biochemistry Faculty ofBiology Justus-Liebig-University-Giessen HDoz. Dr. Michael Niepmann Institute of Biochemistry Faculty of Medicine Justus-Liebig-University-Giessen ________________________________________________________________________ This work was accomplished from December 2001 to November 2005 under the supervision of HDoz. Dr. Michael Niepmann in the group of Prof. Dr. Ewald Beck in the Institute of Biochemistry, Faculty of Medicine, Justus-Liebig-University Giessen. Acknowledgements I would like to specially thank my direct supervisor HDoz. Dr. Michael Niepmann for his constant support, excellent guidance and creative discussions which were the key to my success on the study. Moreover, it is his encouragement and valuable suggestions that gave me motives and inspiration to make progress in my scientific research.