RARβ [RAR-beta] trans-repression of AP-1 transcription factor in HeLa cervical cancer cells [Elektronische Ressource] : consequences on transcription of viral and cellular AP-1 controlled genes / presented by Johanna De Castro Arce

Introduction 3Dissertationsubmitted to theCombined Faculties for the Natural Sciences and for Mathematicsof the Ruperto-Carola University of Heidelberg, Germanyfor the degree ofDoctor of Natural Sciencespresented byJohanna De CastroArce, MSc.BogotÆ, ColombiaOral examinationIntroduction 4RARbbb trans-repression ofAP-1 transcription factorbbin HeLa cervical cancer cells: Consequences on transcription ofviral and cellularAP-1 controlled genesReferees: Prof. Dr. Christine ClaytonProf. Dr. Claus-Hobe Schr derIntroduction 5AcknowledgmentsIwouldliketothankmysupervisorProf.Dr.FrankR slfortheopportunitytojoinhisgroup,forhishelp,guidanceandsupport.Thank to Prof. Dr. Harald zur Hausen for his continuous interest in the development of thiswork.I would like to thank Prof. Dr. Christine Clayton for her support and help in order to reach myPhD.degree.ThankstoProf.Dr.Claus-HobeSchr derforthecorrectionofthismanuscript.IamgratefulltoDr.UbaldoSotoforthetimethatheemployedtohelpmenotonlyintechnicalmatters but also in scientific discussions, thanks for his friendship that was very important formeinaforeigncountry.Iliketothankallthecolleagueswhohelpandsupportmealongthis3years.I want specially thanks my children Daniella andAndrØs Felipe, for all the time that this workdisabled me to be with them. Thanks for their love, patience and confidence. Thanks to myhusbandwhopostponedhisdreamstoallowminescometrue.