Radial oxygen gradients over rat cortex arterioles [Elektronische Ressource] / vorgelegt von Michael Galler

AUS DEM LEHRSTUHL FÜR NEUROCHIRURGIE PROF. DR. MED. ALEXANDER BRAWANSKI DER FAKULTÄT FÜR MEDIZIN DER UNIVERSITÄT REGENSBURG RADIAL OXYGEN GRADIENTS OVER RAT CORTEX ARTERIOLES Inaugural – Dissertation Zur Erlangung des Doktorgrades der Medizin der Fakultät für Medizin der Universität Regensburg vorgelegt von Michael Galler 2011 Dekan: Prof. Dr. Bernhard Weber 1. Berichterstatter: Prof. Dr. Chris Woertgen 2. Berichterstatter: Prof. Dr. Thomas Bein Tag der mündlichen Prüfung: 03.05.2011 Acta NeurochirDOI 10.1007/s00701-010-0777-4CLINICAL ARTICLERadial oxygen gradients over rat cortex arteriolesMichael Galler &Stefan Moritz &Gregor Liebsch &Chris Woertgen &Alexander Brawanski &Jan WarnatReceived: 12 February 2010/Accepted: 12 August 2010# Springer-Verlag 2010Abstract Results Gradient 1 showed significantly different corticalPurpose We present the results of the visualisation of radial pO values between the three different groups. The mean2oxygen gradients in rats’ cortices and their potential use in pO were 2.62, 5.29 and 5.82 mmHg/mm. Gradient2neurocritical management. 2 measured 0.56, 0.90 and 1.02 mmHg/mm respectively.Methods PO maps of the cortex of ten sedated, intubated Gradient 3 showed significant results between the groups2and controlled ventilated Wistar rats were obtained with a with values of 3.18, 6.19 and 6.84 mmHg/mm.camera (SensiMOD, PCO, Kelheim, Germany).