Quantitative modeling of synthetic gene transfer [Elektronische Ressource] / Simon Youssef. Betreuer: Joachim Rädler

Quantitative modeling of synthetic genetransferSimon YoussefM¨unchen 2011Quantitative modeling of synthetic genetransferSimon YoussefDissertationan der Fakult¨at fur¨ Physikder Ludwig–Maximilians–Universit¨atM¨unchenvorgelegt vonSimon Youssefaus Wur¨ zburgMunc¨ hen, den 3.M¨arz 2011Erstgutachter: Prof. Dr. Joachim R¨adlerZweitgutachter: Prof. Dr. Friedrich SimmelTag der mundlic¨ hen Prufung:¨ 10.Mai 2011.Con.tendelingtsClassication1.Zusammenfassung.7t26.5Summary.9lapseI.InmtroEvduction.11en3hingMotiv.ation.11in4expressionOv.erviewof155I.I.Methotds.17.5ofComputational.Moetdeling.approac35hes.17.5.1.Mathematical37vs.ransfercomputationalsinglemo.delsexpressio...7.3.....Assi.t.....29.t.Ev..17.5.2.A32PrimerHandlionAnalysisthe.Gillespie.algorithmdistinction.een.......Discussion...............Gene.Gene.7.118y5.3ellPi-Calculus.allo7.2wsstatean.un.b.ounded.ntheum.b.e.r.ofLinearspgneciesenandProblemreac-.tions........6.3.en.Managemen.and.en.Detection.............6.4.and.ng.Image.Ev.ts.....33.Automatic.b.w.touc.cells......23.I.I6.6I.Results.25.6.Con.text-sensitiv.e.image.ana.lysis.of.single-cell.assa.y.mo.