Quantitative and functional analysis of chromosome dynamics [Elektronische Ressource] : influence of the nucleolus on the regulation of gene expression / Axel B. Berger

Doctorate in molecular cell biology UNIVERSITE PARIS XI UNIVERSITÄT REGENSBURG Ecole Doctorale "Gènes, Génomes, Cellules" Naturwissenschaftliche Fakultät III Presented by : Axel B. Berger To obtain the grade of DOCTEUR de l’Université Paris XI and DOKTOR RER. NAT. der Universität Regensburg Thesis title : Quantitative and functional analysis of chromosome dynamics: Influence of the nucleolus on the regulation of gene expression. Defended on December 12, 2008 Jury : Prof. Giuseppe BALDACCI President Prof. Danièle HERNANDEZ-VERDUN RapporteurDr. Xavier DARZACQapporteurProf. Herbert TSCHOCHNER Thesis Director / Rapporteur Dr. Olivier GADAL ThesisDirector This PhD has been executed at the Institut Pasteur, Department of Cell Biology and Infection, Unité de Biologie Cellulaire du Noyau, Paris, France and the University of Regensburg, Institute for Biochemistry, Genetics and Microbiology, Lehrstuhl für Biochemie III, Regensburg, Germany. The work was supervised by Dr. Olivier Gadal, University of Toulouse, LBME of CNRS, Equipe Organisation et Dynamique Nucléaire, Toulouse, France and Prof. Dr. Herbert Tschochner, University of Regensburg, Institute for Biochemistry, Genetics and Microbiology, Lehrstuhl für Biochemie III, Regensburg, Germany.