Polymer-metallodrug conjugates for cancer diagnostics and therapy [Elektronische Ressource] / submitted by Nadine E. Brückmann

Polymer-Metallodrug Conjugatesfor Cancer Diagnostics and TherapyINAUGURAL DISSERTATIONsubmitted to the faculty ofHeinrich-Heine-Universit¨at Dusseldorf¨Institut fur¨ Anorganische Chemie und StrukturchemieLehrstuhl I: Bioanorganische Chemie and Katalysein partial fulfillment of the requirements for the degree ofDr. rer. nat.submitted byNadine E. Bruc¨ kmannD¨ usseldorf, November 2010Printed with permission of theMathematisch-Naturwissenschaftliche Fakult¨atHeinrich-Heine-Universit¨at Dusseldorf¨Graduate referee: Prof. Dr. Dr. W. Kl¨auiCo-referee: Prof. Dr. C. GanterDate of graduate thesis defense: 13.01.2011IPresentations, Publications and Awards:Presentations (talks and posters):¨Nadine E. Bruckmann, Peter C. Kunz, New Polymer-Metallodrug Conjugates forthCancer Diagnostics,2008,XI InternationalSeminarforPh.D.StudentsonOrganometal-lic and Coordination Chemistry, Sayda, Germany.¨Peter C. Kunz, Nadine E. Bruckmann, Bioorganometallics going Polymer: Usingththe EPR-Effect for Organometallic Drug Targeting,2008,XI SymposiumonMedicinalOrganometallic Chemistry, St. Martin in der Pfalz, Germany.¨Nadine E. Bruckmann, Peter C. Kunz, Hunting for Tumours with FluorescentthPolymers, 2009,11 JCF - Spring Symposium, Essen, Germany.¨Nadine E. Bruckmann, Peter C. Kunz, Fluorescent Polymers for Tumour Diag-thnostics, 2010,ISBOMC10-5 International Symposium on Bioorganometallic Chem-istry, Ruhr-Universit¨at Bochum, Germany.Publications:¨Peter C. Kunz, Nadine E.