Plasma factors as endogenous agonists and modulators of TLR4 signaling in microglia [Elektronische Ressource] / submitted by Jörg Scheffel

Plasma Factors as Endogenous Agonists and Modulators of TLR4 Signaling in Microglia Doctoral Thesis In partial fulfillment of the requirements for the degree “Doctor rerum naturalium (Dr. rer. nat.)” in the Molecular Medicine Study Program at the Georg-August University Göttingen submitted by Jörg Scheffel born in Berlin, Germany Göttingen, April 2010 Members of the Thesis Committee: Supervisor Prof. Dr. U. K. Hanisch Department of Neuropathology University of Göttingen (Medical Faculty) Second member of the Thesis Committee Prof. Dr. J. Wienands Department of Cellular and Molecular Immunology University of Göttingen (Medical Faculty) Third member of the Thesis Committee Prof. Dr. KA. Nave Department of Neurogenetics Max Planck Institute for Experimental Medicine, Göttingen Date of Disputation 21.06.2010 AFFIDAVIT AFFIDAVIT Here, I declare that my doctoral thesis entitled “Plasma Factors as Endogenous Agonists and Modulators of TLR4 Signaling in Microglia” has been written independently with no other sources and aids than quoted. Göttingen, April 2010 (Signature) - I - LIST OF PUBLICATIONS Goos, M., Lange, P., Hanisch, U.K., Prinz, M., Scheffel, J., Bergmann, R., Ebert, S., Nau, R., 2007.