Nanotechnological characterisation of biomaterials [Elektronische Ressource] : structural and biophysical investigations / Stefan Strasser

Nanotechnological Characterisation of Biomaterials – Structural and Biophysical Investigations Dissertation der Fakultät für Geowissenschaften der Ludwig-Maximilians-Universität München Stefan Strasser München, 10. September 2007 Advising supervisor: Prof. Dr. Wolfgang M. Heckl Second supervisor: PD Dr. Albert Zink Date of Disputation: 13. December 2007 Table of Contents Table of Contents 1. Summary.................................................................................................... 4 2. Introduction ............................................................................................... 6 3. Measuring Bioelasticity – A Nanotechnological Approach ................... 8 3.1 Atomic Force Microscopy..................................................................... 8 3.1.1 Imaging Modes.................................................................................... 9 3.1.1.1 Contact Mode ................................................................................... 10 3.1.1.2 Non-Contact Mode............................................................................ 10 3.1.1.3 Intermittent Contact Mode ................................................................. 11 3.1.2 Force Spectroscopy 11 3.1.3 Elasticity Calculations........................................................................ 13 3.1.3.