MTBITC-induced apoptosis and cell cycle arrest of human hepatoma (HepG2) cells [Elektronische Ressource] : a link between p53 and human telomerase ? / vorgelegt von Evelyn Lamy

MTBITC-induced apoptosis and cellMTBITC-induced apoptosis and cellcycle arrest of human hepatoma(HepG2) cells:(HepG2) cells:A link between p53 and human telomerase ?Inaugural - Dissertationzur Erlangung des Grades einer Doktors der Humanbiologie (Dr. biol. hom.)des Fachbereichs Humanmedizinder Justus-Liebig-Universität Gießenvorgelegt von: Evelyn Lamyaus: SaarbrückenGiessen im Jahr 2007Aus dem Institut für Innenraum- und Umwelttoxikologiedes Fachbereichs Humanmedizin der Justus-Liebig-Universität GießenDirektor: Prof. Dr. V. Mersch-Sundermann1. Gutachter: Univ. Prof. Dr. med. V. Mersch-Sundermann2. Gutachter: Univ. Prof. Dr. med. A. ReiterTag der Disputation: 26.5.2008 Meinen Eltern & AlexanderEs ist nicht genug zu wissen, man muss es auch anwenden; es ist nicht genug zu wollen, man muss es auch tun. Johann Wolfgang von GoetheAcknowledgements iACKNOWLEDGEMENTSThis thesis grew out of a series of dialogues with my supervisor Professor Dr. Volker Mersch-Sundermann, who gave me every opportunity to broaden my educational horizon and to develop my personality. He piqued my curiosity and provoked me in his very special manner to keep on track. I honestly could not have imagined having had a better mentor; his common-sense, his occasional cracking-of-the-whip, but also his patience with me is greatly appreciated. Especially his axioms will inspire me - or rather haunt me - for the rest of my life.