Monitoring and characterization of T-lymphocyte reconstitution after allogeneic stem cell transplantation [Elektronische Ressource] / vorgelegt von Ahmad Abu-Khader

Monitoring and Characterization ofT-Lymphocyte Reconstitution afterAllogeneic Stem Cell TransplantationDISSERTATION ZUR ERLANGUNG DES DOKTORGRADES DERNATURWISSENSCHAFTEN (DR.RER.NAT.) DER FAKULTÄT III- BIOLOGIE UND VORKLINISCHE MEDIZIN -DER UNIVERSITÄT REGENSBURGvorgelegt vonAhmad Abu-KhaderausAmman – JordanienFebruar / 2006The work presented in this thesis was carried out in the Department of Hematology andOncology at the University Hospital Regensburg from February 2004 to March 2006.Parts of this work will be presented in:nd32 Annual Meeting of the European Group for Blood and Marrow Transplantation,Hamburg, Germany, March 19-22 2006.Promotionsgesuch eingereicht am: 16.02.2006Die Arbeit wurde angeleitet von: Prof. Dr. med. Ernst HollerPrüfungsausschuss:Vorsitzender: Prof. Dr. Richard Warth1. Gutachter: Prof. Dr. Hans Kalbitzer2. Gutachter: Prof. Dr. Ernst Holler3. Prüfer: Prof. Dr. Ralph WitzgallTomy parents,my wife Reem,my twins Jana and Mutazandfor the coming twins.____________________________________________________________Table of ContentsTable of ContentsPage1 Introduction........................................................................................... 11.1 Stem cell transplantation (SCT)........................................................... 11.1.1 Stem Cell Sources................................................................................... 21.1.2 Autologous SCT................................................