Žmonių plikimas ir mikroelementų pusiausvyros sutrikimas: priežastys ir reikšmė ; Alopecia in humans and balance of trace elements: causes and significance

KAUNAS UNIVERSITY OF MEDICINE Rima Naginien ė ALOPECIA IN HUMANS AND BALANCE OF TRACE ELEMENTS: CAUSES AND SIGNIFICANCE Doctoral dissertation Biomedical Sciences, Biology (01 B) Kaunas, 2005 KAUNO MEDICINOS UNIVERSITETAS Rima Naginien ė ŽMONI Ų PLIKIMAS IR MIKROELEMENT Ų PUSIAUSVYROS SUTRIKIMAS: PRIEŽASTYS IR REIKŠM Ė Daktaro disertacija Biomedicinos mokslai, biologija (01 B) Kaunas, 2005 2The dissertation accomplished in the Laboratory for Environmental Health Research, Institute for Biomedical Research, Kaunas University of Medicine in 2000 – 2004 years. Scientific supervisor: Assoc. Prof. Dr. Olegas Abdrachmanovas (Kaunas University of Medicine, Biomedical Sciences, Biology – 01 B) 3CONTENT 1. SYMBOLS AND ABBREVIATIONS 6 2. INTRODUCTION 7 3. OBJECTIVE AND THE TASKS 10 4. LITERATURE OVERVIEW 11 4.1 Hair 11 4.2 diseases 13 4.3 Alopecia areata 14 4.4 Trace elements 18 4.5 Lead 20 4.6 Manganese 22 4.7 Chromium 24 4.8 Cadmium 25 4.9 Mercury 27 4.10 Copper 29 4.11 Zinc 31 5. MATERIAL AND METHODS 34 5.1 Subjects 34 5.2 Material and methods 35 5.3 Statistical analysis 37 6. RESULTS AND DISCUSSION 38 6.1 Alopecia in Lithuania 6.1.