Molecular genetic of prostate cancer [Elektronische Ressource] : association of the candidate genes CYP17 and MSR1 / submitted by Zorica Vesovic

University of Ulm Department of Human Genetics Head: Prof. Dr. Walther Vogel Molecular genetic of prostate cancer: association of the candidate genes CYP17 and MSR1 Thesis presented to the Faculty of Medicine, University of Ulm, to obtain the degree of a Doctor of Human Biology submitted by Zorica Vesovic from Belgrade 2005 Amtierender Dekan: 1. Berichterstatter: 2. Berichterstatter: Tag der Promotion: Table of contents 1. Introduction........................................................................................................... 1 1.1. Epidemiology of prostate cancer and risk factors ........................................................... 1 1.1.1. Incidence of prostate cancer and PSA influence...................................................... 1 1.1.2. Age and Ethnicity..................................................................................................... 2 1.1.3. Diet........................................................................................................................... 2 1.1.4. Vitamin D................................................................................................................. 3 1.1.5. Role of hormones in prostate cancer........................................................................ 4 1.1.6. Familial aggregation....................................................