Modulation der Expression von Enzymen der Isoprenoidsynthese: Effekte auf die Vγ9V_d632-T-Zellaktivierung und das Tumorzellwachstum [Elektronische Ressource] = Modulating the expression of enzymes of isoprenoid synthesis: effects on Vγ9V_d632 T-cell activation and tumor cell growth / submitted by Jianqiang Li

MODULATION DER EXPRESSION VON ENZYMEN DER ISOPRENOIDSYNTHESE: EFFEKTE AUF DIE Vγ9Vδ2 T ZELLAKTIVIERUNG UND DAS TUMORZELLWACHSTUM MODULATING THE EXPRESSION OF ENZYMES OF ISOPRENOID SYNTHESIS: EFFECTS ON V γ9V δ2 T CELL ACTIVATION AND TUMOR CELL GROWTH Doctoral thesis for a doctoral degree at the Graduate School of Life Sciences, Julius-Maximilians-Universität Würzburg, Section of Infection and Immunity Submitted by JIANQIANG LI From Hebei, China Würzburg, 2009 Submitted on: …………………………………………………………..…….. Office stamp Members of the Promotionskomitee:  Chairperson: Prof. Thomas Müller Primary Supervisor: Prof. Thomas Herrmann Supervisor (Second): Prof. Roland Benz Supervisor (Third): Prof. Alexander Steinle Date of Public Defence: …………………………………………….………… Date of Receipt of Certificates: ………………………………………………. 谨将此论文献给我亲爱的妻子和女儿! This work is dedicated to my wife Haiming and my daughter Zhiyu whose sacrifices, which were realized by our loss of precious time together, were for me the most painful and humbling of all ！ ACKNOWLEDGMENTS  First of all, I would like to gratefully acknowledge the enthusiastic supervision of Prof. Dr.