Zika lié à un cas de meningoencephalite

T h e n e wj o u r n a le n g l a n do f m e d i c i n e C o r r e s p o n d e n c e Zika Virus Associated with Meningoencephalitis To the Editor:virus (ZIKV) is currently Zika spreading widely, while its clinical spectrum remains a matter of investigation. Evidence of a A C D relationship between ZIKV infection and cerebral 1,2 3 birth abnormalitiesis growing.An increased incidence of some peripheral nervous syndromes B Figure 1. Imaging of the Brain. MRI with the use of fluid-attenuated inversion recovery (FLAIR) imaging revealed subcortical white-matter hyperintensities in the right frontal region, the right parietal region (Panel A), the right temporo-occipital region (Panel B), and bilateral rolandic regions (Panel A). The slight hyperintensity of the right rolandic fissure (Panel A, arrow) is suggestive of meningitis. The multiple punctuated hyperintensities on diffusion-weighted sequences are suggestive of ischemic foci (Panel C). The MRI with FLAIR imaging and diffusion-weighted sequences were performed with the use of a 3T MRI unit (Magnetom Verio, Siemens). The computed tomographic angiogram shows an irregular narrowing of the right callosomarginal artery (Panel D, arrows). Angiography was performed with the use of a Discovery CT750 HD scanning system (GE Medical Systems). n engl j med nejm.org The New England Journal of Medicine Downloaded from nejm.org on March 11, 2016. For personal use only. No other uses without permission.