GENOTONORM - GENOTONORM 07122011 AVIS CT5437

Introduction GENOTONORM 12 mg, powder and solvent for solution for injection B/1 cartridge of 12 mg and 1 ml of solvent (CIP code: 341 996-9) GENOTONORM 5.3 mg, powder and solvent for solution for injection B/1 cartridge of 5.3 mg of powder and 1 ml of solvent (CIP code: 349 755-0) GENOTONORM MINIQUICK 0.2 mg, powder and solvent for solution for injection B/7 cartridges of 0.2 mg and 0.25 ml with syringes (CIP code: 343 842-9) GENOTONORM MINIQUICK 0.4 mg, powder and solvent for solution for injection B/7 cartridges of 0.4 mg and 0.25 ml with syringes (CIP code: 343 843-5) GENOTONORM MINIQUICK 0.6 mg, powder and solvent for solution for injection B/7 cartridges of 0.6 mg and 0.25 ml with syringes (CIP code: 343 844-1) GENOTONORM MINIQUICK 0.8 mg, powder and solvent for solution for injection B/7 cartridges of 0.8 mg and 0.25 ml with syringes (CIP code: 343 845-8) GENOTONORM MINIQUICK 1 mg, powder and solvent for solution for injection B/7 cartridges of 1 mg and 0.25 ml with syringes (CIP code: 343 846-4) GENOTONORM MINIQUICK 1.2 mg, powder and solvent for solution for injection B/7 cartridges of 1.2 mg and 0.25 ml with syringes (CIP code: 343 847-0) GENOTONORM MINIQUICK 1.4 mg, powder and solvent for solution for injection B/7 cartridges of 1.4 mg and 0.25 ml with syringes (CIP code: 343 848-7) GENOTONORM MINIQUICK 1.6 mg, powder and solvent for solution for injection B/7 cartridges of 1.6 mg and 0.25 ml with syringes (CIP code: 343 849-3) GENOTONORM MINIQUICK 1.8 mg, powder and solvent for solution for injection B/7 cartridges of 1.8 mg and 0.25 ml with syringes (CIP code: 343 850-1) GENOTONORM MINIQUICK 2 mg, powder and solvent for solution for injection B/7 cartridges of 2 mg and 0.25 ml with syringes (CIP code: 343 851-8) Posted on Apr 17 2013 Active substance (DCI) somatropin Pédiatrie - Mise au point Maintien de l’avis favorable au remboursement chez l’enfant non déficitaire en hormone de croissanceProgrès thérapeutique mineur dans l’insuffisance rénale chronique, le syndrome de Turner et le syndrome de Prader-WilliPas d’avantage clinique démontré dans le déficit du gène SHOX et chez les enfants nés petits pour l’âge gestationnel (SGA) Sept spécialités d’hormone de croissance (GH) synthétique ont l'AMM chez l’enfant dans une ou plusieurs situations en l’absence de déficit en GH (voir tableau) : syndrome de Turner, insuffisance rénale chronique, enfants nés petits pour l’âge gestationnel n'ayant pas rattrapé ce retard à l’âge de 4 ans ou plus (SGA), syndrome de Prader-Willi, déficit du gène SHOX.Le gain de taille obtenu avec la GH est de faible amplitude et la démonstration de cette efficacité est de faible niveau de preuve.L’intérêt clinique de la GH est faible dans le SGA, modéré dans le déficit en gène SHOX et important dans le syndrome de Turner, le syndrome de Prader-Willi et l’insuffisance rénale chronique.Dans toutes les situations cliniques, le risque de surmortalité observé chez des adultes majoritairement déficitaires ayant été traités par GH dans l’enfance doit rendre la prescription prudente.Pour en savoir plus télécharger la synthèse ou les avis GENOTONORM, NORDITROPINE, NUTROPINAQ, OMNITROPE, SAIZEN, UMATROPE, ZOMACTON ATC Code H01AC01 Laboratory / Manufacturer PFIZER GENOTONORM 12 mg, powder and solvent for solution for injection B/1 cartridge of 12 mg and 1 ml of solvent (CIP code: 341 996-9) GENOTONORM 5.3 mg, powder and solvent for solution for injection B/1 cartridge of 5.3 mg of powder and 1 ml of solvent (CIP code: 349 755-0) GENOTONORM MINIQUICK 0.2 mg, powder and solvent for solution for injection B/7 cartridges of 0.2 mg and 0.25 ml with syringes (CIP code: 343 842-9) GENOTONORM MINIQUICK 0.4 mg, powder and solvent for solution for injection B/7 cartridges of 0.4 mg and 0.25 ml with syringes (CIP code: 343 843-5) GENOTONORM MINIQUICK 0.6 mg, powder and solvent for solution for injection B/7 cartridges of 0.6 mg and 0.25 ml with syringes (CIP code: 343 844-1) GENOTONORM MINIQUICK 0.8 mg, powder and solvent for solution for injection B/7 cartridges of 0.8 mg and 0.25 ml with syringes (CIP code: 343 845-8) GENOTONORM MINIQUICK 1 mg, powder and solvent for solution for injection B/7 cartridges of 1 mg and 0.25 ml with syringes (CIP code: 343 846-4) GENOTONORM MINIQUICK 1.2 mg, powder and solvent for solution for injection B/7 cartridges of 1.2 mg and 0.25 ml with syringes (CIP code: 343 847-0) GENOTONORM MINIQUICK 1.4 mg, powder and solvent for solution for injection B/7 cartridges of 1.4 mg and 0.25 ml with syringes (CIP code: 343 848-7) GENOTONORM MINIQUICK 1.6 mg, powder and solvent for solution for injection B/7 cartridges of 1.6 mg and 0.25 ml with syringes (CIP code: 343 849-3) GENOTONORM MINIQUICK 1.8 mg, powder and solvent for solution for injection B/7 cartridges of 1.8 mg and 0.25 ml with syringes (CIP code: 343 850-1) GENOTONORM MINIQUICK 2 mg, powder and solvent for solution for injection B/7 cartridges of 2 mg and 0.25 ml with syringes (CIP code: 343 851-8) Posted on Apr 17 2013