Mechanisms of transcriptional stalling and mutagenesis at DNA lesions [Elektronische Ressource] / Gerke E. Damsma

Dissertation zur Erlangung des Doktorgrades der Fakultät für Chemie und Pharmazie der Ludwig-Maximilians-Universität München Mechanisms of transcriptional stalling and mutagenesis at DNA lesions Gerke E. Damsma aus Hellendoorn, Niederlande 2009 II Erklärung Diese Dissertation wurde im Sinne von §13 Abs. 3 der Promotionsordnung vom 29. Januar 1998 von Herrn Prof. Dr. Patrick Cramer betreut. Ehrenwörtliche Versicherung Diese Dissertation wurde selbständig und ohne unerlaubte Hilfe erarbeitet. München, am 26. November 2009 Gerke Damsma Dissertation eingereicht am 26. November 2009 1. Gutachter: Prof. Dr. Patrick Cramer 2. Gutachter: Prof. Dr. Dietmar Martin Mündliche Prüfung am 27. Januar 2010 III Acknowledgements First and most of all, I want to thank Patrick for giving me the opportunity to work in his lab and for his continuous personal support. His excitement about science and his encouraging and respectful attitude towards his co-workers create an extremely pleasant and motivating atmosphere in the lab. This was crucial for keeping my motivation high and turning my efforts into success. I am thankful to all present and former members of the Cramer lab for their highly collaborative attitude and all their help, for inspiring scientific discussions and for the great times together.