Mechanisms of assembly and activity dependent remodelling of the presynaptic cytomatrix at the active zone [Elektronische Ressource] / von Vesna Lazarevic

“Mechanisms of assembly and activity-dependent remodelling of the presynaptic cytomatrix at the active zone ” Dissertation zur Erlangung des akademischen Grades doctor rerum naturalium (Dr. rer. nat.) genehmigt durch die Fakultät für Naturwissenschaften der Otto-von-Guericke-Universität Magdeburg von Dipl. Mol. Biol. Vesna Lazarevic geb.am 02.06.1978 in Belgrade, Serbia Gutachter: Prof. Dr. Eckart D. Gundelfinger Prof. Dr. Susanne Schoch McGovern eingericht am: 20.10.2009 vorteidigt am: 04.03.2010 Acknowledgement The work presented in this dissertation was carried out during the years 2006-2009 in the Department of Neurochemistry and Molecular Biology, Leibniz Institute for Neurobiology, Magdeburg, Germany. I would like to thank my supervisor Prof. Dr. Eckart D. Gundelfinger for the opportunity to do my doctoral thesis under his guidance. My special thanks go to Dr. Anna Fejtova for constant support, help and encouragement during my PhD thesis. Many thanks to Dr. Stefano Romorini and Dr. Wilko Altrock and to all members of Bassoon group (Dasha, Markus, Anne, Alexandra, Diana, Daniela, and Claudia) for fruitful discussions, help and nice atmosphere in the lab. Thank to Cornelia Schoene, former diploma student in our lab, who did all electrophysiology work discussed in the theses. I would like also to thank Dr.