Isolation and characterization of (S)-chelianthifoline synthase, (S)-stylopine synthase and two FAD oxidases from a cDNA library from Argemone mexicana [Elektronische Ressource] / von María Luisa Díaz Chávez

Isolation and characterization of (S)-chelianthifoline synthase, (S)-stylopine synthase and two FAD oxidases from a cDNA library from Argemone mexicana Dissertation zur Erlangung des akademischen Grades doctor rerum naturalium (Dr. rer. nat.) vorgelegt an der Naturwissenschaftlichen Fakultät I-Biowissenschaften der Martin-Luther-Universität Halle-Wittenberg Fachbereich Biochemie / Biotechnologie von Frau María Luisa Díaz Chávez geboren am 25.03.1974 in Mexiko Gutachter: 1. Prof. Dr. Toni M. Kutchan 2. Prof. Dr. Jörg Degenhardt 3. Prof. Dr. Ute Wittstock Halle, den 22. Januar 2009 urn:nbn:de:gbv:3-000015158[ http://nbn-resolving.de/urn/resolver.pl?urn=nbn%3Ade%3Agbv%3A3-000015158 ] This work was supported by DAAD/CONACyT and PROMEP/UAEM Content Content CONTENT……………………………………………………………………………………. I ABBREVIATIONS ………………………………………......………...………………….. IV 1. INTRODUCTION..................................................................................................1 1.1. Alkaloids.................................................................................................................... 1 1.1.1. Benzylisoquinoline alkaloids ................................................................................. 1 1.1.2. Biosynthesis of berberine and sanguinarine........................................................... 3 1.2. Cytochrome P450.......................................................