Ion channels in mixed tethered bilayer lipid membranes [Elektronische Ressource] / vorgelegt von Jing Li-Fries

Ion Channels in Mixed Tethered Bilayer Lipid Membranes Dissertation zur Erlangung des Grades “Doktor der Naturwissenschaften” am Fachbereich Biologie der Johannes Gutenberg-Universität Mainz vorgelegt von Jing Li-Fries geboren in Beijing, V. R. China Mainz, July 2007 Table of Contents 1. Introduction ...............................................................................................................1 1.1. Biological membranes .................................................................................... 1 1.1.1 Structure and functions………………………………….………..1 1.1.2 Structure and properties of membrane lipids…………………......2 1.2. Model systems of the biological membrane .............................................. ... 3 1.2.1 Liposomes……………………………………………………… . 4 1.2.2 Black lipid bilayer membranes………………………………….. 5 1.2.3 Supported lipid bilayer membranes……………………………... 6 1.2.4 Polymer-supported bilayer lipid membranes................................ 7 1.2.5 Tethered lipid bilayer membranes………………………………. 8 1.3. Motivation ..................................................................................................... ..10 2. Ion channels.........................................................................................................12 2.1. Overview........................................................................