Investigations of a bio-synthetic approach to access large padlock as a part of a new concept for detecting DNA on a microarray [Elektronische Ressource] / submitted by Rijuta Kotenkar

“Investigations of a bio-synthetic approach to access large padlock as a part of a new concept for detecting DNA on a microarray” Dissertation submitted as a partial fulfillment for procuring the degree Doctor of Natural Science (Dr. rer. nat.) Faculty of Biology and Chemistry University of Bremen Submitted by Rijuta Kotenkar Bremen 2008 iExamination Committee First Examiner: Prof. Dr. Dietmar Blohm Biotechnologie und Molekulare Genetik, Universität Bremen Second Examiner: Prof. Dr. Annette Becker Molekulare Genetik/Evolutionäre Entwicklungsgenetik, Universität Bremen Additional Examiner I: Prof. Dr. Jörn Bullerdiek Zentrum für Humangenetik (ZHG), Universität Bremen Additional Examiner II: Dr. Sascha Todt Zentrums für Technomathematik (ZeTeM), Universität Bremen Student Member I: Dipl. biol. Frank Rühle PhD student, Universität Bremen Student Member II: Manawa Diwekar Master student, Universität Bremen Public Defence: st1 of December 2008, Monday ii This thesis was envisioned as a part of the Sixth Framework Programme grant of the European Commission, “GENSENSOR-NANOPARTS”, titled “Nano-biotechnical components of an advanced bioanalytical microarray system”. The work was completed and written at the department of Biotechnologie und Molekulare Genetik, Universität Bremen.