Intra- and intercellular trafficking of the prion protein [Elektronische Ressource] / presented by Edwin Schiff

UNIVERSITE PARIS VI-PIERRE ET MARIE CURIEECOLE DOCTORALE DE PHYSIOLOGIE ET PATHOPHYSIOLOGIEUNIVERSITÄT REGENSBURGNATURWISSENSCHAFTLICHE FAKULTÄT III-BIOLOGIE UNDVORKLINISCHE MEDIZINYear 2007Dissertationfor obtaining the grade of Doctor of the University Paris VI and the University ofRegensburgpresented byEDWIN SCHIFF10.12.2007Intra- and intercellular trafficking of the prion proteinSupervisors: Dr. Daniela Männel and Dr. Chiara ZurzoloThesis committee:Mr. Korth Carsten RapporteurMr. Lazarow PaulMrs. Rousset Monique ExaminerMr. Tanner WidmarMrs. Männel Daniela Thesis supervisorMrs. Zurzolo ChiaraThe most exciting phrase to hear in science, the one that heralds newdiscoveries, is not 'Eureka!' (I found it!) but 'That's funny ...'Isaac AsimovI was gratified to be able to answer promptly. I said I don't know.Mark TwainAcknowledgements, remerciements, Danksagungen:I would like to thank first of all my two supervisors.Without Chiara’s drive, support and most importantly immensepatience with me, I wouldn’t be writing these acknowledgements formy own thesis, because there wouldn’t be any. I know that it wasn’teasy for her and she certainly grew a few grey hairs due to me. Sorryfor that. On the other hand, we also set free a lot of positive energy,which ended in quite a good job, I think. I truly hope that we willmanage to bring the submitted manuscripts to a good end.