Induction and regulation of plasma membrane blebbing by SH4 domains and the diaphanous related formin FHOD1 [Elektronische Ressource] / presented by Sebastian Hannemann

Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences Induction and Regulation of Plasma Membrane Blebbing by SH4-Domains and the Diaphanous Related Formin FHOD1 presented by Diplom-Biologe Sebastian Hannemann born in: Hildesheim, Germany Oral-examination: Referees: Prof. Dr. Hans-Georg Kräusslich Prof. Dr. Oliver Till Fackler Meiner Familie Goethe, 1808 "Grau, teurer Freund, ist alle Theorie, Und grün des Lebens goldner Baum." Johann Wolfgang von Goethe Faust, der Tragödie erster Teil, Studierzimmer INDEX 1 PUBLICATIONS.........................................................................................................I 2 ABBREVIATIONS......................................................................................................II 3 SUMMARY...............................................................................................................1 4 ZUSAMMENFASSUNG ...............................................................................................3 5 INTRODUCTION........................................................................................................5 5.1 The Microfilament System......