Impact of the epithelial hypoxia-inducible factor 2 {α [alpha], fetal liver kinase-1 system on murine lung development [Elektronische Ressource] / by Katrin Ahlbrecht

Impact of the epithelial hypoxia-inducible factor 2 α/ fetal liver kinase-1 system on murine lung development Inaugural Dissertation Submitted to the Faculty of Medicine in partial fulfilment of the requirements for the PhD degree of the Faculties of Veterinary Medicine and Medicine of the Justus Liebig University Giessen by Katrin Ahlbrecht, M.D. of Kassel Giessen 2008 From the Department of Internal Medicine Medical Clinic and Policlinic II University Giessen Lung Center Director/Chairman: Prof. Werner Seeger, M.D. of the Medical Faculty of the Justus Liebig University Giessen First Supervisor and Committee Member: Prof. Werner Seeger, M.D. Second Supervisor and Committee Member: Dr. Robert Voswinckel, M.D. Committee Members: Prof. Dr. Wolfgang Kummer, M.D. Prof. Dr. Lienhard Schmitz, PhD. Prof. Dr. Robert Bals, M.D. th Date of Doctoral Defense: March 12 2009 3 Table of Contents LIST OF FIGURES..................................................................................................... 7 LIST OF TABLES ...................................................................................................... 9 1. INTRODUCTION .................................................................................................. 10 1.1. Lung development........................................................................................................................................