Hsp70 response to electrical stimulation in C2C12 cells [Elektronische Ressource] / presented by Lei Wang

University of ULM Department of Internal Medicine II Section of Sports and Rehabilitation Medicine (Head: Prof. Dr. Jürgen M. Steinacker) Hsp70 Response to Electrical Stimulation in C2C12 cells Dissertation for the attainment of the Doctoral Degree of Medicine (Dr. med.) at the Faculty of Medicine, University of Ulm, Ulm, Germany Presented by Lei Wang Born in Jinzhou, Liaoning Province, P.R.China 2008 Amtierender Dekan: Prof. Dr. Klaus-Michael Debatin 1. Berichterstatter: Prof. Dr. Yuefei Liu 2. Berichterstatter: Prof. Dr. E. Marion Schneider Tag der Promotion: 20.06.2008 Content Content Abbreviations……………………………………………………………… IV 1 Introduction........................................................................................... 1 1.1 Concept of Hsp70 ................................................................................. 1 1.2 Regulation of cellular Hsp70 response in skeletal muscle ............... 1 1.2.1 Inducing factors of Hsp70 response................................................... 2 1.2.2 Influencing factors of Hsp70 response............................................... 3 1.2.3 Regulation of Hsp70 at different levels............................................... 4 1.2.4 Mechanisms underlying regulation of Hsp70..................................... 6 1.3 Functions of Hsp70 ............