High-throughput experimentation for microscale cultivations and recombinant protein expression [Elektronische Ressource] / vorgelegt von Robert Huber

High-Throughput Experimentation for Microscale Cultivations and Recombinant Protein Expression Von der Fakultät für Mathematik, Informatik und Naturwissenschaften der RWTH Aachen University zur Erlangung des akademischen Grades eines Doktors der Naturwissenschaften genehmigte Dissertation vorgelegt von Dipl.-Ing. (FH), M. Systems Eng. Robert Huber aus Mainburg Berichter: Prof. Dr.-Ing. J. Büchs Prof. Dr. U. Schwaneberg Tag der mündlichen Prüfung: 19.4.2010 Diese Dissertation ist auf den Internetseiten der Hochschulbibliothek online verfügbar. Preface Preface This thesis was conducted at the RWTH Aachen University, AVT-Biochemical Engineering from June 2006 to September 2009. The project was financially supported by the Stiftung Industrieforschung (Project S735) and the companies Protagen, Henkel and m2p-labs. I am grateful to Prof. J. Büchs for the opportunity to conduct my PhD thesis at his department and for his continual support and good advice throughout this work. Furthermore, I wish to thank Prof. U. Schwaneberg and Prof. L. Elling for accepting to be members of my thesis committee and for fruitful discussions. For the excellent collaboration during the project I particularly want to thank P. Weirich, M. Schwarz, C. Gutjahr, K. Schulte, J. Beator, R. Stehr, S. Evers, L. Maksym, K.H.