Greedy phylogeny-based orthology assignment and its application to the evolutionary analysis of metabolic coupling [Elektronische Ressource] / Sabine Thuß. Betreuer: Martin Lercher

Greedy phylogeny-based orthology assignment and its application to the evolutionary analysis of metabolic coupling Inaugural-Dissertation zur Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakultät der Heinrich-Heine-Universität Düsseldorf vorgelegt von Sabine Anita Christiane Thuß aus Zwickau Düsseldorf, April 2011 aus dem Institut für der Heinrich-Heine Universität Düsseldorf Gedruckt mit der Genehmigung der Mathematisch-Naturwissenschaftlichen Fakultät der Heinrich-Heine-Universität Düsseldorf Referent: Prof. Dr. Martin Lercher Koreferent: r. William Martin Tag der mündlichen Prüfung: 27. 05. 2011 Declaration This thesis is submitted for the degree of Doctor rerum naturalium at the Heinrich-Heine-University Düsseldorf. It has not been submitted to any other university for a degree. I agree that the University library may lend out or copy this thesis freely. Sabine Anita Thuß. April, 2011. Acknowledgements: At first I would like to thank my supervisor Prof. Dr. Martin Lercher for giving me the opportunity to work in my favourite scientific field of evolutionary biology in combination with bioinformatics. Thank you, Martin, for the scientific support over all this time and the interesting and motivating discussions we had. Additionally, I wish to thank Prof.