Genetic, biochemical, and electron microscopic analysis of components involved in transcription coupled mRNA export [Elektronische Ressource] / presented by Maria Luisa Oppizzi

DissertationSubmitted to theCombined Faculties for the Natural Sciences and for Mathematicsof the Ruperto-Carola University of Heidelberg, Germanyfor the Degree ofDoctor of Natural SciencesPresented byDiplom-Biologin: Maria Luisa OppizziBorn in : Milan, ItalyOral examination :Genetic, Biochemical and Electron Microscopic Analysisof Components Involved in Transcription-Coupled mRNAExportReferees: Prof. Dr. Ed HurtDr. Anne EphrussiAcknowledgementsI would like to thank Ed Hurt for giving me the possibility to work on this project and forbeing always available to discuss it. I would also like to thank all the members of the lab forcreating a nice and interactive environment.Grazie alla mia numerosa famiglia, che mi sostiene sempre con forza e amore, anche dalontano. E alle mie angeli custodi, Alessia, Alessandra e Simona. Grazie per aver creduto inme in quest’avventura. Sarebbe stata molto piu’ dura senza sapervi e sentirvi vicine. Grazieanche a tutti i fantastici amici che sono rimasti a Milano, ma hanno la pazienza di seguirmisempre per e-mail.Of course, a very big thank to the great friends I met in the lab and in Heidelberg. Silvi,Vikram, Susana, Kiki, Tracy, Alex, Oliver and Maribel, thank you for the friendly atmospherein the lab and for sharing with me so many moments during these years. It was great to workwith you and to have fun together.